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Aging is wild. One day you’re doing handstands in the grass, the next you’re Googling “why does my knee sound like popcorn?” A lot of our aches and pains come down to inflammation—the bloating, brain fog, random rashes, and that lovely mid-afternoon crash. To combat it all, I created this anti-inflammatory smoothie recipe using plant-based ingredients that combat inflammation and are packed with nutrients.

Anti-inflammatory smoothie with berries on top on a slate board

Why You’ll Love It

  • It tastes like a tropical treat. Earthy beets and baby kale get totally balanced out by sweet pineapple, mixed berries, and fresh orange—bright, tangy, and surprisingly smooth.
  • It helps calm everyday inflammation. Each ingredient is chosen to support your joints, digestion, and energy—from ginger and berries to chia seeds and leafy greens.
  • It’s a 5-minute reset. Perfect after a long run, a Costco marathon, or anytime your body needs a little extra love without any fuss.
  • It’s nutrient-dense without being heavy. Fiber, antioxidants, and healthy fats come together in a refreshing, 16-oz blend your body will thank you for.

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Ingredients to make anti-inflammatory smoothie recipe on table ready to blend

Ingredients You’ll Need

Sip on this smoothie with fresh beets, citrus fruits and anti-inflammatory ginger to recover from a Saturday morning shopping trip to Costco (never a good idea), a long run with your bestie or just another day living la vida loca. Here’s what goes into your glass, how each ingredient tastes and blends, plus the nutrition perks they bring to the party:

  • Baby kale: Earthy and mildly grassy leafy green vegetable, kale blends best when mixed with liquid first. It’s rich in antioxidants like vitamin C and flavonoids that help reduce inflammation.
  • Beets: Sweet, earthy, and vibrant, beets add natural color and depth. They contain betalains—powerful anti-inflammatory compounds that support heart health.
  • Oranges: Bright and juicy, oranges balance earthy flavors and create a silky texture. Their vitamin C helps reduce inflammation and support immune health.
  • Mixed Berries: Tart and jammy, berries thicken smoothies while delivering anthocyanins, potent antioxidants linked to reduced inflammation.
  • Pineapple: Sweet with a hint of tang, pineapple blends smoothly and contains bromelain, an enzyme known for its anti-inflammatory and digestive benefits. If using fresh pineapple, cut pineapple and then freeze to chill the smoothie before blending.
  • Ginger Root: Warm and spicy, ginger adds bold flavor in small amounts. Its gingerols are known to help reduce inflammation and muscle soreness.
  • Coconut Oil: Lightly sweet and creamy, coconut oil blends best when softened. This healthy fat contains lauric acid, which may support immune and anti-inflammatory pathways.
  • Chia Seeds: This superfood naturally thicken smoothies and provide omega-3s, fiber, and protein to support inflammation balance and fullness.

Dietary Adjustments & Substitutions

Need to swap an ingredient or accommodate a food allergy? Click the button below for tailored suggestions just for you:

How to Make Anti-Inflammatory Smoothie

  1. Prep your produce. Wash and chop the kale and beets. Peel the orange and remove any seeds so it’s ready for the blender. Check out my recommended blenders for smoothies.
  2. Blend the base. Add the kale, chopped beets, peeled orange, and water to your blender. Blend on high until everything is completely smooth, scraping down the sides if needed.
  3. Add the fruit and flavor boosters. Toss in the frozen mixed berries, frozen pineapple, fresh ginger root, chia seeds, and coconut oil (if using).
  4. Blend until creamy. Blend again on high until the smoothie is thick, creamy, and no chunks remain. If it’s too thick, add a splash more water and blend again.
  5. Pour and enjoy. Pour into your favorite glass or jar. Garnish with extra chia seeds or a slice of orange if you’re feeling fancy, then sip right away for the biggest nutritional boost.

Time-Saving Tip

Instead of adding multiple ingredients to your blender every time, you drop an anti-inflammatory blender bomb into your smoothie to boost anti-inflammatory support.

If you make this anti-inflammatory smoothie recipe, I’d love to hear how it turned out in the comment box below. Your feedback helps me and all the readers in this community. And if you’re interested in more plant-based recipes (and exclusive content), sign up for my weekly recipe newsletter.

Two glasses full of anti-inflammatory smoothie topped with berries.
4.95 (37 votes)

Anti-Inflammatory Smoothie

Blend this anti-inflammatory smoothie with earthy beets, spicy ginger, and sweet pineapple coming together to support your body from the inside out. Kale and chia seeds pack in fiber, omega-3s, and nutrients your joints and hormones will thank you for.
Prep: 3 minutes
Blend: 2 minutes
Total: 5 minutes
Serves: 1
Author: Jen Hansard

Ingredients 

  • ½ cup kale
  • ½ cup beets peeled and chopped
  • ¾ cup water
  • ½ orange peeled
  • 1 cup mixed berries frozen
  • ½ cup pineapple frozen
  • 1 teaspoon ginger root peeled
  • 2 tablespoon chia seeds
  • 1 teaspoon coconut oil optional
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Instructions 

  • Add kale, beets, water and orange to blender container.
  • Puree on high until the mixture is smooth. Scrape down the sides of chunks of the green stick to the sides of the blender.
  • Add remaining ingredients and blend again on high until everything is well combined and smooth.

Helpful Tools

Notes

  • Carrots can be substituted for the beets.
  • Mango can be substituted for the pineapple.
  • Baby kale or spinach can be used to make the smoothie less bitter.
  • Use at least one frozen fruit for a refreshingly cool smoothie.

Nutrition

Serving: 16 oz | Calories: 336 kcal | Carbohydrates: 55 g | Protein: 7 g | Fat: 13 g | Saturated Fat: 4 g | Polyunsaturated Fat: 6 g | Monounsaturated Fat: 1 g | Trans Fat: 0.03 g | Sodium: 74 mg | Potassium: 656 mg | Fiber: 18 g | Sugar: 32 g | Vitamin A: 1351 IU | Vitamin C: 92 mg | Calcium: 244 mg | Iron: 3 mg

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Common Questions

Do anti-inflammatory smoothies actually taste good?

Yes—anti-inflammatory smoothies taste amazing when you balance earthy ingredients (like kale or beets) with naturally sweet fruits (like pineapple, orange, or berries). A little ginger or citrus helps brighten everything up too.

How often should I drink an anti-inflammatory smoothie?

You can have this smoothie every single day, yet feel free to start with just a few times a week to see how your body adjusts. This can be a powerful addition to your routine if you’re working on reducing inflammation.

What helps if I taste the kale or beets in smoothie?

To mask the taste of beets or leafy greens, add more ginger, pineapple, orange, or berries to help cut the “earthiness.”

Can I prep this smoothie in advance?

Yes, you can make this anti-inflammatory smoothie in advance to save time. Blend it the night before and refrigerate in a sealed jar (drink within 24 hours). Or try freezing meal prep smoothie packs with pre-measured ingredients and dump them into the blender when ready. Another options is to make smoothie cubes (freeze the smoothie in an ice tray) and re-blend with liquid when needed.


FREE! Smoothie + Meal Plan

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4.95 from 37 votes (22 ratings without comment)

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Comments

  1. Hi new follower
    I was wondering if I can swap coconut oil for almond butter. I do intermittent fasting and usually add a nut butter to my smoothies. Also can I swap the banana for half of a avocado so that I can lower the sugar intake? Thanks in advance.

    1. Hey Lina! So glad you’re blending with us! Since this Anti-Inflammatory Smoothie is a bit more tropical leaning in taste, we’re not sure that almond butter would work – yet, if you enjoy the smoothie as-is, we think it’d be great to eat a few whole almonds (or other nut of your choice) on the side as part of your meal. Since this is one of our rare recipes that is banana free, def feel free to add some avocado to up the creaminess factor, as well as healthy fats, etc. Avocado could be used in place of the coconut oil as well. Happy blending!

    1. Beetroot powder is an excellent swap in for smoothies and 1 tsp usually equals about one beet. However, you’ll be consuming less fiber with this substitution, so that’s something to keep in mind.

    1. Hi, Jen.

      Does the beet need to be pre-cooked or can we use raw beet?

      Thanks & be well!

      Ari

    2. Excellent question Ari! It’s gonna be up to you here. You can use either cooked (steamed is best) or raw beets. Cooked beets you’ll find slightly sweeter + easier to peel. Raw beets will be earthy in flavor.

    1. Hi Maree! Currently the postal service is not allowing us to ship to Australia and several other countries due to covid protocols. We’re super sad about it, yet are continuing to check the status and will start shipping to Australia as soon as we’re able.

  2. Can you freeze these ingredients without th water and then use at a later date and just add the water when needed.

  3. Hi I haven’t tried it before but I do want to started it yet but I can not have coconut due to my allergic reaction towards it what can I substitute with it instead and still get the same results.

    1. Hi Tina! So sorry we missed your question earlier! You can use another mild oil like grapeseed oil. Since other oils are in liquid form, it might be best to reduce the amount slightly for this recipe. Another swap could be applesauce. Let us know what you try and what you liked!

    2. Will turmeric be a good substitute for ginger and taste as good? Can’t stand ginger.

    3. Love this question Brian! And you’re not alone. Ginger seems to be a love it or hate it kinda thing. While turmeric has even more anti-inflammatory properties, we’re not sure how it would do taste-wise in this recipe. If you give it a blend, def let us know what you think!

  4. You say that your fat burning smoothie yields l smoothie. It seems to me that it should be for 2. I easily fill a 16 Oz glass. Isn’t that a lot for 1 person?

    1. Hey there Ada! Most of our smoothie recipes make a 16 oz. smoothie – which is one portion. Our goal for you is to add one 16-ounce green smoothie to your day in addition to your regular diet. We found that amount helps to get the optimal amount of added nutritional benefit from the greens and fruit being blended. You can drink it with a meal, as a meal, or as a snack. If it’s too much for you, you could def drink half at one time of day and half later or even the next day.

    1. Hey rawkstar! Fresh turmeric would make a great sub here, if you can tolerate it. Turmeric has really lovely anti-inflammatory properties as well.

  5. 5 stars
    Wow! Thank you for sharing this recipe. I’ve recently been diagnosed with mild Chron’s disease. I do not want to be on any medications and an asymptotic for the most part. So I am trying to heal my body as naturally as possible. I have introduced more fiber in my diet (which I’m already seeing positive results from!), and plan on eating as many anti-inflammatory foods/shakes as I can tolerate to help balance my system again! The ginger in this shake really sets it off, I think! Thanks again.

    1. So sorry to hear about your recent diagnosis, Diana. Yet, super proud of you for seeking natural solutions! All the best as you step toward healing.

  6. Do you cook the beet or is it raw? If you cook it, what is the best way without losing all the nutrients?

    1. Totally your choice, Amy! You can use either cooked (steamed is best) or raw beets here. Raw beets have a more earthy flavor. Cooked beets area slightly sweeter + are easier to peel.

    1. Hi Mary Jane! Generally speaking, it’s totally fine to exchange water and plant-based milk for each other in any recipe. However, depending on the smoothie it can affect the taste. Plant-milk usually does better in smoothies that aren’t citrus based. Since this is a mix of citrus and berry – we say go for it! Give it a blend and let us know what you think. 🙂 We would def avoid traditional cow’s milk dairy here as it can increase inflammation in many cases.

    1. Kale would make a great swap here. It’s even higher in flavonoids, which give it more anti-inflammatory super powers!

    1. Hi Dorothy – You can totally use either raw or steamed. Raw beets are a bit more earthy while roasted, steamed or cooked beets have a slightly sweeter taste and are easier to peel.

  7. I cannot have pineapples, are there any good replacements? 🙂 Looking forward to trying this!

    1. Oranges, mangoes or peaches are great subs for pineapple. Happy blending!

    1. Hi Kathleen! Great question – the beets you find in a jar are similar in nutritional properties, yet will contain more sodium than fresh. And yeah, you do lose additional nutrients (like vitamin A and C, plus antioxidants) when you avoid the skin, yet it’s def better than no beets at all!

  8. It took me several rounds of buying the fresh ingredients before I tried making this smoothie. I found that my beets went bad after 2-3 days, so if i didn’t make it right away, they’d be rotten. BUT, I finally got the beets and kale at the same time and whipped up a batch of this stuff. I admit, I expected it to be gross and earthy-tasting, but none-the-less, good for me. WRONG – it’s actually delicious! The pineapple and berries do alot to “cover up” any beet taste, and the beets add the most beautiful color! It is so good, it’s more like drinking kool-aid than it is like drinking V8. Don’t be scared. I felt stronger and really smart 😉 almost immediately after drinking a batch!

    1. I think you could drink one of these every day if you like, Ronae. 🙂

    1. Hey Bob! Everyone’s body is different so I can’t really say how long it will take. I think if you’re dealing with inflammation, you’ll want to drink this smoothie at least a few times a week and alternate with other green smoothies. You could start feeling better in as short as a few days. Good luck!